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Doxycycline Hyclate

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Ngalan sa API	Indikasyon	Espesipikasyon	US DMF	EU DMF	Ang CEP
Doxycycline Hyclate	Antibiotics	USP/EP	13771	√

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Background

Ang Doxycycline hyclate kay usa ka antibiotic [1].

Ang Doxycycline hyclate usa ka gigikanan sa tetracycline ug adunay mga kalihokan nga anti-inflammatory ug antimicrobial.Gipugngan sa Doxycycline ang pagkopya sa virus sa dengue sa vitro sa paagi nga nagsalig sa temperatura.Ang bili sa IC50 mao ang 52.3μM sa 37°C ug 26.7μM sa 40°C.Gipugngan niini ang dengue virus pinaagi sa pagpugong sa NS2B-NS3 serine protease sa virus.Ang 60μM nga doxycycline nagpamenos sa CPE sa DNEV2-infected nga mga selula [1].

Ang Doxycycline nakit-an nga usa ka tigpugong sa MMP.Ang pagtambal sa Doxycycline makapakunhod sa lebel sa MMP-8 ug -9 ug makapugong sa pagpahayag sa tisyu nga MMP-2 ug MMP-9.Dugang pa, ang pagtambal sa doxycycline hinungdanon nga pagkunhod sa insidente sa intracranial aneurysms.Ang Doxycycline gikataho usab nga usa ka anti-inflammatory agent base sa pagdili niini sa matrix metalloproteinases.Dugang pa, ang doxycycline adunay kusog nga antimalarial nga kalihokan nga adunay IC50 nga kantidad nga 320nM sa 96h in vitro [2, 3].

Mga pakisayran:
[1] Rothan HA, Mohamed Z, Paydar M, Rahman NA, Yusof R. Inhibitory nga epekto sa doxycycline batok sa dengue virus replication in vitro.Arko Virol.2014 Abr;159(4):711-8.
[2] Maradni A, Khoshnevisan A, Mousavi SH, Emamirazavi SH, Noruzijavidan A. Papel sa matrix metalloproteinases (MMPs) ug MMP inhibitors sa intracranial aneurysms: usa ka review nga artikulo.Med J Islam Repub Iran.2013 Nob;27(4):249-254.
[3] Draper MP, Bhatia B, Assefa H, Honeyman L, Garrity-Ryan LK, Verma AK, Gut J, Larson K, Donatelli J, Macone A, Klausner K, Leahy RG, Odinecs A, Ohemeng K, Rosenthal PJ, Nelson ML.In vitro ug in vivo antimalarial efficacies sa optimized tetracyclines.Mga Ahente sa Antimicrob Chemother.2013 Hul;57(7):3131-6.

Deskripsyon

Ang Doxycycline (hyclate) (Doxycycline hydrochloride hemiethanolate hemihydrate), usa ka antibiotic, usa ka oral nga aktibo ug broad-spectrum metalloproteinase (MMP) inhibitor [1].

Klinikal nga Pagsulay

Numero sa NCT	Sponsor	kahimtang	Petsa sa Pagsugod	hugna
NCT00246324	Louisiana State University Health Sciences Center Shreveport\|Biogen	Daghang Sclerosis	Disyembre 2003	Yugto 4
NCT00910715	University Medical Center Ljubljana	Erythema Chronicum Migrans	Hunyo 2009	Dili Magamit
NCT00243893	Unibersidad sa California, San Francisco\|National Institute of Neurological Disorders and Stroke (NINDS)	Aneurysms\|Mga Arteriovenous Malformation	Hulyo 2004	Yugto 1
NCT00126399	CollaGenex Pharmaceuticals	Rosacea	Hunyo 2004	Yugto 3
NCT01318356	Radboud University\|ZonMw: Ang Netherlands Organization for Health Research and Development	Q Fever\|Fatigue Syndrome, Chronic\|Coxiella Infection	Abril 2011	Yugto 4
NCT00177333	Unibersidad sa Pittsburgh	Aborsyon, Naaghat\|Pagsuka	Septiyembre 2005	Yugto 4
NCT00007735	US Department of Veterans Affairs\|Pfizer\|United States Department of Defense\|VA Office of Research and Development	Persian Gulf Syndrome\|Mga Impeksyon sa Mycoplasma	Enero 1999	Yugto 3
NCT00351273	Unibersidad sa South Florida\|National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)	Arthritis, Reaktibo\|Reiter nga Sakit	Mayo 2006	Yugto 3
NCT00469261	Careggi Hospital	Myocardial Infarction\|Pagbag-o sa Wala nga Ventricular	Mayo 2007	Yugto 2
NCT00547170	Unibersidad sa Pittsburgh\|Tu Du Hospital	Endometritis	Enero 2007	Yugto 4
NCT01475708	University Medical Center Ljubljana	Lyme Borreliosis	Mayo 2011
NCT01368341	Morten Lindbaek\|Norwegian Institute of Public Health\|Sorlandet Hospital HF\|Norwegian University of Life Sciences\|University of Oslo	Erythema Migrans\|Erythema Chronicum Migrans\|Borreliosis\|Lyme Disease\|Sayo nga Lyme Disease	Hunyo 2011	Yugto 4
NCT02538224	Islamic Azad University, Tehran	Laygay nga Periodontitis	Hulyo 2013	Phase 2\|Phase 3
NCT00066027	Unibersidad sa Nebraska\|National Institute of Dental and Craniofacial Research (NIDCR)	Periodontitis	Hunyo 2002	Yugto 3
NCT00376493	Hospital de Clinicas de Porto Alegre	Septic Aborsyon	Mayo 2006	Yugto 4
NCT03448731	Fundacion CRIS de Investigación para sa Vencer el Cáncer\|Amgen\|Apices Soluciones SL	Pagkahilo sa Panit	Mayo 10, 2018	Yugto 2
NCT00989742	Unibersidad sa Nottingham	Lymphangioleiomyomatosis\|Tuberous Sclerosis	Hulyo 2009	Yugto 4
NCT01438515	Horizon Health Network	Methicillin-resistant nga Staphylococcus Aureus	Agosto 2008	Dili Magamit
NCT02929121	Ang Task Force for Global Health\|United States Agency for International Development (USAID)	Lymphedema\|Lymphatic Filariasis\|Filariasis	Enero 15, 2019	Yugto 3
NCT00952861	Odense University Hospital\|Kolding Sygehus\|Svendborg Hospital\|Fredericia Hospital\|Naestved Hospital\|Hillerod Hospital, Denmark\|Rehiyon Syddanmark\|Danmarks Lungeforening\|Danish National Research Foundation	Sakit sa Pulmonary, Laygay nga Obstructive	Oktubre 2009	Yugto 4
NCT00138801	Sorlandet Hospital HF	Lyme Neuroborreliosis	Marso 2004	Yugto 3
NCT00942006	University Medical Center Ljubljana	Gisuspetsahan nga Early Lyme Neuroborreliosis	Hulyo 2009	Dili Magamit
NCT02713607	Unibersidad sa California, Davis	Acne vulgaris	Marso 2016	Phase 1\|Phase 2
NCT00560703	Galderma	Blepharitis\|Meibomianitis\|Mauga nga Mata	Nobyembre 2007	Yugto 2
NCT01014260	Johns Hopkins University	Sakit sa kasingkasing	Septiyembre 2010	Yugto 4
NCT00000938	National Institute of Allergy and Infectious Diseases (NIAID)	Sakit nga Lyme		Yugto 3
NCT01398072	University College, London\|Royal Free Hampstead NHS Trust\|University of Cambridge\|National Institute for Health Research, United Kingdom	Chronic Obstructive Pulmonary Disease (COPD).	Disyembre 2011	Yugto 3
NCT03479502	Vanderbilt University Medical Center\|Orthopedic Research and Education Foundation	Adhesive Capsulitis\|Adhesive Capsulitis of Unspecified Shoulder\|Frozen Shoulder	Enero 5, 2018	Yugto 4
NCT02929134	Ang Task Force for Global Health\|United States Agency for International Development (USAID)	Lymphedema\|Lymphatic Filariasis\|Filariasis	Pebrero 16, 2018	Yugto 3
NCT00480532	Oregon Health ug Science University	Mga kontraseptibo, Oral	Mayo 2007	Dili Magamit
NCT01594827	Johns Hopkins University\|Case Western Reserve University\|Cystic Fibrosis Foundation	Cystic Fibrosis	Oktubre 2012	Yugto 2
NCT01744093	Weill Medical College sa Cornell University\|National Heart, Lung, and Blood Institute (NHLBI)	HIV\|Chronic Obstructive Pulmonary Disease (COPD)\|Emphysema	Hulyo 17, 2014	Dili Magamit
NCT03530319	National Taiwan University Hospital	Pneumonia, Mycoplasma	Nobyembre 10, 2018	Dili Magamit
NCT04167085	Unibersidad sa California, Los Angeles	Epistaxis	Disyembre 18, 2017	Yugto 4
NCT01411202	Ottawa Hospital Research Institute	Malignant nga Pleural Effusion	Hunyo 2011	Yugto 2
NCT01474590	Galderma	bugasbugas	Nobyembre 2011	Yugto 3
NCT00649571	Mylan Pharmaceuticals	Himsog	Hulyo 2005	Yugto 1
NCT02899000	Galderma Laboratories, LP	Acne vulgaris	Hulyo 29, 2016	Yugto 4
NCT00538967	Leiden University Medical Center	Aortic aneurysm, tiyan	Mayo 2002	Yugto 2
NCT00439400	Alacrity Biosciences, Inc.	Mamala nga Mata	Pebrero 2007	Yugto 2
NCT00917553	Thomas Gardner\|Penn State University\|Juvenile Diabetes Research Foundation\|Milton S. Hershey Medical Center	Diabetic Retinopathy	Hulyo 2009	Yugto 2
NCT00495313	CollaGenex Pharmaceuticals	Rosacea	Marso 2007	Yugto 4
NCT01855360	Brigham ug Women's Hospital	amyloidosis;Kasingkasing (Pagpadayag)\|Senile Cardiac Amyloidosis	Hunyo 2013	Phase 1\|Phase 2
NCT00419848	Shahid Beheshti University of Medical Sciences	bugasbugas	Agosto 2006	Yugto 2
NCT03532464	Ospital sa Unibersidad, Bordeaux\|USC EA 3671 Mga impeksyon sa tawo sa mycoplasmes ug chlamydiae	Chlamydia Trachomatis Infection\|Impeksyon sa Babae\|Impeksyon sa Anal	Hulyo 1, 2018	Yugto 4
NCT02756403	Medstar Health Research Institute\|Society of Family Planning	Unang Trimester Aborsyon	Marso 2016	Dili Magamit
NCT00353158	National Institute of Arthritis ug Musculoskeletal and Skin Diseases (NIAMS)\|National Institutes of Health Clinical Center (CC)	Himsog nga mga Boluntaryo\|Mga Impeksyon sa Fungal\|Mga Impeksyon sa Bakterya	Hulyo 11, 2006	Yugto 1
NCT01317433	Institut Cancerologie de l'Ouest	Colorectal Cancer Metastatic\|Kahilo sa Balat	Disyembre 2010	Yugto 3
NCT01658995	Petra M. Casey\|Mayo Clinic	Pagdugo nga may kalabotan sa ESI	Septiyembre 13, 2012	Yugto 3
NCT03968562	State University sa New York - Downstate Medical Center	Mga pantal	Mayo 15, 2019	Yugto 2
NCT02569437	Icahn School of Medicine sa Mount Sinai	Polyp sa Ilong Sinus	Septiyembre 2014	Yugto 2
NCT01198509	NYU Langone Health\|National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)\|Memorial Sloan Kettering Cancer Center	Rheumatoid Arthritis\|Psoriatic Arthritis\|Periodontal Disease	Enero 2010	Dili Magamit
NCT01163994	University Medical Center Ljubljana	Daghang Erythema Migrans	Hunyo 2010	Dili Magamit
NCT02388477	Milton S. Hershey Medical Center	Samad sa Rotator Cuff		Dili Magamit
NCT01010295	International Extranodal Lymphoma Study Group (IELSG)	Non-Hodgkin Lymphoma	Septiyembre 2006	Yugto 2
NCT00775918	Ranbaxy Laboratories Limited\|Ranbaxy Inc.	Himsog	Hunyo 2005	Dili Magamit
NCT04050540	Unibersidad sa Washington\|Kenya Medical Research Institute\|Kenya National AIDS & STI Control Programme\|University of California, San Francisco\|National Institute of Allergy and Infectious Diseases (NIAID)	Mga Impeksyon sa HIV\|HIV+AIDS\|Impeksyon sa Neisseria Gonorrheae\|Impeksyon sa Chlamydia Trachomatis\|Impeksyon sa Syphilis	Pebrero 5, 2020	Yugto 4
NCT02562651	Russian nga Academy sa Medical Sciences	Mga Sakit sa Vascular\|Mga Sakit sa Cardiovascular\|Acute Myocardial Infarction	Pebrero 2014	Phase 2\|Phase 3
NCT00001101	National Institute of Allergy and Infectious Diseases (NIAID)	Sakit nga Lyme		Yugto 3
NCT00340691	National Institute of Allergy and Infectious Diseases (NIAID)\|National Institutes of Health Clinical Center (CC)	Impeksyon sa Mansonella Perstans\|Mp Microfilaremia	Disyembre 6, 2004	Yugto 2
NCT01112059	Unibersidad sa Alabama sa Birmingham\|Cystic Fibrosis Foundation	Cystic Fibrosis	Nobyembre 2008	Dili Magamit
NCT00652704	Par Pharmaceutical, Inc.\|Anapharm	Aron Madeterminar ang Bioequivalence Ubos sa Kondisyon sa Fed	Hulyo 1999	Yugto 1
NCT01783860	Tehran University of Medical Sciences	Posterior Blepharitis	Enero 2013	Yugto 2
NCT02564471	State University of New York - Upstate Medical University\|Walter Reed Army Institute of Research (WRAIR)\|Kansas State University	Rabies	Abril 2016	Yugto 4
NCT04206631	Unibersidad sa Indonesia	Acne vulgaris	Abril 1, 2015	Yugto 1
NCT03956446	University Medical Center Ljubljana\|University of Ljubljana School of Medicine, Slovenia	Tick Borne Encephalitis	Septiyembre 1, 2014	Dili Magamit
NCT03960411	Felix Chikita Fredy, MD\|National Cardiovascular Center Harapan Kita Hospital Indonesia\|Indonesia University	ST Elevation Myocardial Infarction\|Anterior Wall Myocardial Infarction\|Kapakyasan sa Kasingkasing\|Remodeling, Ventricular	Mayo 25, 2019	Yugto 3
NCT00322465	National Institute of Allergy and Infectious Diseases (NIAID)	Uretritis	Nobyembre 2006	Yugto 2
NCT01375491	University of California, San Diego\|Ruth L. Kirschstein National Research Service Award\|National Institute of Diabetes ug Digestive and Kidney Diseases (NIDDK)\|National Center for Research Resources (NCRR)	Type 2 Diabetes\|Pagtambok	Oktubre 2009	Yugto 4
NCT03478436	Medical University of Vienna\|Dr.Ang Reddy's Laboratories Limited	Rosacea	Hulyo 2016	Yugto 1
NCT01207739	Radboud University\|Sint Maartenskliniek\|ZonMw: Ang Netherlands Organization for Health Research and Development	Sakit sa Lyme\|Impeksyon sa Borrelia	Septiyembre 2010	Yugto 4
NCT00939562	Pfizer	Bakterya nga Impeksyon	Nobyembre 2008	Yugto 4
NCT03608774	National Institute of Allergy and Infectious Diseases (NIAID)	Anal Chlamydia Infection	Hunyo 26, 2018	Yugto 4
NCT02281643	Kwame Nkrumah University of Science and Technology\|University of Bonn\|Heinrich-Heine University, Duesseldorf	Mansonella Perstans Infection\|Buruli Ulcer\|Tuberculosis\|Co-infection	Oktubre 2014	Yugto 2
NCT00066066	Ang Forsyth Institute\|National Institute of Dental and Craniofacial Research (NIDCR)	Periodontitis\|Mga Sakit sa Periodontitis	Hulyo 2003	Yugto 2
NCT01798225	Medical University of South Carolina\|National Center for Research Resources (NCRR)	Sakit nga Periodontal\|Type 2 Diabetes Mellitus	Disyembre 2007	Yugto 4
NCT00612573	Warner Chilcott	Acne vulgaris	Pebrero 2008	Yugto 2
NCT01631617	National Institute of Arthritis ug Musculoskeletal and Skin Diseases (NIAMS)\|National Institutes of Health Clinical Center (CC)	Eczema\|Dermatitis\|Mga Sakit sa Panit, Genetic\|Dermatitis, Atopic\|Mga Sakit sa Balat	Septiyembre 18, 2012	Yugto 2
NCT03173053	Radboud University\|ZonMw: The Netherlands Organization for Health Research and Development\|Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)\|Aalborg University Hospital\|Rigshospitalet, Denmark	Staphylococcus Aureus\|Disorder sa Motility	Pebrero 8, 2018	Dili Magamit
NCT00715858	McMaster University\|The Physicians' Services Incorporated Foundation	Sakit nga Alzheimer	Mayo 2008	Yugto 3
NCT03584919	University Medical Center Ljubljana	Erythema Chronicum Migrans	Hunyo 1, 2006	Dili Magamit
NCT01469585	Unibersidad sa Hawaii\|Charles Drew University of Medicine ug Science\|Meharry Medical College	Pagdugo sa Breakthrough	Nobyembre 2011	Dili Magamit
NCT02759120	Weill Medical College sa Cornell University\|Duke Clinical Research Institute\|University of Chicago\|University of Washington\|University of Pittsburgh\|National Heart, Lung, and Blood Institute (NHLBI)	Idiopathic Pulmonary Fibrosis	Marso 22, 2017	Yugto 3
NCT02735837	Amirhossein Farahmand\|Islamic Azad University, Tehran	Diabetes Mellitus nga adunay Sakit nga Periodontal	Enero 2015	Phase 2\|Phase 3
NCT03655197	Unibersidad sa California, Davis	Rosacea\|Ocular Rosacea\|Cutaneous Rosacea	Nobyembre 2, 2017	Unang Phase 1
NCT01188954	Northwell Health	Seroma	Enero 2010	Dili Magamit
NCT00388778	Shahid Beheshti University of Medical Sciences	Bugas\|Paghubag	Oktubre 2005	Phase 2\|Phase 3
NCT01087476	Metropolitan Autonomous University\|Instituto Nacional de Cancerologia de Mexico	Mucositis	Mayo 2010	Yugto 2
NCT02174757	Ang CD Pharma India Pvt.Ltd.\|Sree Mookambika Institute of Dental Sciences	Laygay nga Periodontitis	Agosto 2014	Yugto 3
NCT03911440	National Taiwan University Hospital	Atypical Pneumonia	Nobyembre 10, 2018	Dili Magamit
NCT02553083	Rabin Medical Center	Impeksyon sa Bakterya Tungod sa Helicobacter Pylori (H. Pylori)	Oktubre 22, 2015	Yugto 4
NCT04234945	Ahmadu Bello University Teaching Hospital	Infertility, Babaye\|Pelvic Inflammatory Disease	Enero 13, 2020	Dili Magamit
NCT00892281	Galderma Laboratories, LP	Rosacea	Abril 2009	Yugto 4
NCT02913118	Qingfeng Pharmaceutical Group	Community Acquired Pneumonia	Hulyo 2016	Yugto 4
NCT04153604	Sistema sa Panglawas sa Methodist	Cirrhosis\|Spontaneous Bacterial Peritonitis	Nobyembre 4, 2019
NCT03153267	University Medical Center Ljubljana\|University of Ljubljana School of Medicine, Slovenia	Erythema Chronicum Migrans	Hunyo 1, 2017	Dili Magamit
NCT03116659	James J. Peters Veterans Affairs Medical Center	Lymphoma, T-Cell, Cutaneous	Pebrero 1, 2018	Unang Phase 1
NCT03401372	Jian Li\|Peking University First Hospital\|Chinese PLA General Hospital\|Beijing Chao Yang Hospital\|West China Hospital Affiliate sa Sichuan University\|Tongji Hospital Affiliate sa Tongji Medical College of HUST\|Union Hospital Affiliate sa Tongji Medical College of HUST\|Shanghai Changzheng Hospital\| Nanfang Hospital sa Southern Medical University\|Peking Union Medical College Hospital	amyloidosis;Sistemiko	Abril 21, 2018	Dili Magamit
NCT01380496	Par Pharmaceutical, Inc.\|Anapharm	Aron Madeterminar ang Bioequivalence Ubos sa Kondisyon sa Fed	Nobyembre 1999	Yugto 1
NCT03083197	Unibersidad sa Oxford\|Shoklo Malaria Research Unit\|Chiangrai Prachanukroh Hospital	Scrub Typhus	Oktubre 15, 2017	Yugto 4
NCT00237016	Medical Corps, Israel Defense Force	Nagbalikbalik nga Hilanat, Tick-Borne\|Jarisch Herxheimer Reaction	Abril 2002	Phase 2\|Phase 3
NCT01308619	Galderma Laboratories, LP	Rosacea	Abril 2011	Yugto 4
NCT01198912	Ospital sa Unibersidad, Ghent	Laygay nga Rhinosinusitis\|Polip sa Ilong	Nobyembre 22, 2011	Yugto 2
NCT02016365	Unibersidad sa Umeå	Transthyretin amyloidosis \| Cardiomyopathy	Pebrero 2012	Yugto 2
NCT00783523	Unibersidad sa California, San Francisco	Arteriovenous Malformations\|Cavernous Angiomas\|Brain Aneurysms	Marso 2008	Yugto 1
NCT03337932	University Medical Center Ljubljana	Erythema Chronicum Migrans	Enero 1, 2018	Dili Magamit
NCT00568711	Dong-Min Kim\|Chosun University Hospital	Scrub Typhus	Septiyembre 2006	Dili Magamit
NCT01874860	Unibersidad sa Louisville \| James Graham Brown Cancer Center	Colorectal Cancer\|Ulo ug Liog nga Kanser	Agosto 2013	Yugto 2
NCT01171859	IRCCS Policlinico S. Matteo	Transthyretin amyloidosis	Hulyo 2010	Yugto 2
NCT01653522	Ang Cleveland Clinic	Migraine Disorder\|Labad sa Ulo, Migraine\|Migraine\|Migraine Sakit sa Ulo\|Migraine Uban sa Aura\|Migraine nga Walay Aura\|Mga Sakit sa Ulo, Panguna	Hulyo 2012	Dili Magamit
NCT01820910	International Extranodal Lymphoma Study Group (IELSG)	Marginal Zone Lymphoma sa Ocular Adnexal	Marso 2013	Yugto 2
NCT01323101	Unibersidad sa Southern California	Cystic Fibrosis	Abril 2008	Yugto 4
NCT00829764	Teva Pharmaceuticals USA	Himsog	Oktubre 2006	Yugto 1
NCT01668498	AIO-Studien-gGmbH	Ras-wildtype nga Colorectal Cancer	Mayo 2011	Yugto 2
NCT01030666	Peter Eickholz\|Heidelberg University\|Dr.August Wolff GmbH & Co. KG Arzneimittel\|Gaba International AG\|Goethe University	Periodontitis	Abril 2007	Yugto 4
NCT00012688	US Department of Veterans Affairs\|Colgate-Periogard-Dentsply\|VA Office of Research and Development	Diabetes Mellitus\|Kabus nga Glycemic Control\|Peridontal Disease		Dili Magamit
NCT01885910	Derm Research, PLLC\|WFH MEDICAL, LLC	Acne vulgaris	Hulyo 2013	Yugto 4
NCT02328469	University Medical Center Ljubljana\|Slovenian Research Agency\|University of Ljubljana School of Medicine, Slovenia\|Harvard University	Aseptic nga meningitis	Hunyo 2014
NCT00355602	Unibersidad sa Dundee\|Tenovus Scotland	Colitis, Ulcerative	Hulyo 2006	Dili Magamit
NCT02606032	Hamilton Health Sciences Corporation\|Hamilton Academic Health Sciences Organization	Ulcerative Colitis	Mayo 2016	Yugto 2
NCT01465802	Pfizer	Dili Gamay nga Cell Lung Cancer (NSCLC)	Disyembre 26, 2011	Yugto 2
NCT02623959	MD Anderson Cancer Center	Mga Advanced nga Kanser\|Malignant Pleural Effusions	Abril 27, 2016	Yugto 4
NCT03481972	IRCCS Policlinico S. Matteo	TTR Cardiac amyloidosis	Abril 11, 2018	Yugto 3
NCT00428818	University of Texas Southwestern Medical Center	Impeksyon	Agosto 2005	Dili Magamit
NCT01935622	Virginia Commonwealth University	Non-ischemic Cardiomyopathy\|Systolic Heart Failure (NYHA II-III)	Hulyo 2012	Yugto 2
NCT01886560	Unibersidad sa Sun Yat-sen	Pagsunog sa Mata	Septiyembre 2013	Phase 2\|Phase 3
NCT04239755	Unibersidad sa Damanhour\|Universidad sa Tanta	Traumatic Brain Injury	Disyembre 15, 2019	Yugto 4
NCT02204254	Center Hospitalier Universitaire de Nice	Rosacea	Marso 2014	Dili Magamit
NCT00837213	Stiefel, usa ka GSK Company\|GlaxoSmithKline	bugasbugas	Agosto 2007	Yugto 4
NCT03115177	Rush University Medical Center	Osteoarthritis	Nobyembre 2015	Dili Magamit
NCT03618108	Cadrock Pty. Ltd.\|Sentro sa Digestive Diseases, Australia	Coronary Heart Disease\|Mga Impeksyon sa Chlamydophila Pneumoniae	Abril 4, 2018	Yugto 2
NCT03435952	MD Anderson Cancer Center\|BioMed Valley Discoveries, Inc\|Merck Sharp & Dohme Corp.	Malignant Neoplasm sa Dughan\|Malignant Neoplasms sa Digestive Organs\|Malignant Neoplasms sa Utok sa Mata ug Ubang Bahin sa Central Nervous System\|Malignant Neoplasms sa Babaye Genital Organs\|Malignant Neoplasms sa Ill-defined Secondary and Unspecified Sites\|Malignant Neoplasms of Independent Mga Dapit\|Malignant Neoplasms sa Lip Oral Cavity ug Pharynx\|Malignant Neoplasms sa Lalake Genital Organs\|Malignant Neoplasms sa Mesothelial ug Soft Tissue\|Malignant Neoplasms sa Respiratory ug Intrathoracic Organs\|Malignant Neoplasms sa Thyroid ug Ubang Endocrine Neoplasms sa Urinaryoplasms Tracts\|Malignant Neoplasms sa Respiratory ug Intrathoracic Organs	Hulyo 10, 2018	Yugto 1
NCT01867294	Academic ug Community Cancer Research United\|National Cancer Institute (NCI)	Advanced nga Malignant Neoplasm\|Dermatologic Complication	Agosto 31, 2012	Yugto 2
NCT01677286	Unibersidad sa Boston	Amyloidosis	Hulyo 2012	Yugto 2
NCT00511875	Thomas Gardner\|Juvenile Diabetes Research Foundation\|Milton S. Hershey Medical Center	Diabetic Retinopathy	Hulyo 2008	Yugto 2
NCT04108897	Johns Hopkins University	Rosacea	Septiyembre 17, 2019	Unang Phase 1
NCT00631501	Kaunas University of Medicine\|University Hospital, Linkoeping	Lateral Epicondylalgia (Tennis Elbow)		Dili Magamit
NCT02203682	Unibersidad sa Sun Yat-sen	Graves Ophthalmopathy\|Mga Sakit sa Graves\|Mga Sakit sa Mata\|Mga Sakit sa Thyroid\|Mga Sakit sa Sistema sa Endocrine\|Mga Sakit sa Mata, Panulundon\|Hyperthyroidism\|Mga Sakit sa Autoimmune\|Mga Sakit sa Immune System	Hulyo 2014	Yugto 2
NCT02005653	Indian Council of Medical Research	Filarial;Infestation	Pebrero 2009	Yugto 4
NCT03585140	Centro Dermatológico Dr. Ladislao de la Pascua	Acne Vulgaris\|Pagbag-o sa Pagkaon	Enero 1, 2016	Dili Magamit
NCT02147262	University Medical Center Ljubljana\|University of Ljubljana School of Medicine, Slovenia\|Medical University of Vienna\|Harvard University	Laygay nga Atrophic Acrodermatitis	Hulyo 2013	Dili Magamit
NCT02220751	Unibersidad sa Sao Paulo\|Fundação de Amparo à Pesquisa do Estado de São Paulo	Periodontitis\|Type 2 nga Diabetes Mellitus	Marso 2009	Yugto 3
NCT01825408	Unibersidad sa North Carolina, Chapel Hill	Sinusitis	Pebrero 2013	Yugto 4
NCT02884713	King Faisal Specialist Hospital & Research Center	GASTRITIS	Hunyo 2013	Dili Magamit
NCT02726646	Unibersidad sa Campinas, Brazil\|Pontificia Universidade Catolica de Sao Paulo	Laygay nga Periodontitis	Hunyo 2015	Yugto 2
NCT00883818	Samsung Medical Center	Sobra-aktibo nga pantog	Enero 2007	Yugto 4
NCT00829790	Teva Pharmaceuticals USA	Himsog	Oktubre 2006	Yugto 1
NCT01949233	Unibersidad sa Oxford\|Oxford University Hospitals NHS Trust	Marfan Syndrome	Oktubre 2013	Yugto 2
NCT01518192	University Medical Center Ljubljana\|Slovenian Research Agency	Erythema Migrans\|Mga Sintomas sa Post-Lyme Disease	Hunyo 2006	Yugto 4
NCT02845024	Islamic Azad University, Tehran	Diabetes Mellitus nga adunay Sakit nga Periodontal	Septiyembre 2014	Dili Magamit
NCT01879930	University Hospital Inselspital, Berne	Laygay nga Pelvic Pain Syndrome\|Bladder Pain Syndrome	Nobyembre 2012	Yugto 4
NCT00041977	CollaGenex Pharmaceuticals	Acne Rosacea	Hunyo 2002	Yugto 3
NCT02341209	Rochester General Hospital	Cutaneous T-cell Lymphoma\|Mycosis Fungoides\|Sezary Syndrome	Pebrero 6, 2018	Yugto 2
NCT00002872	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)\|North Central Cancer Treatment Group	Metastatic nga Kanser	Nobyembre 1996	Yugto 3
NCT03162497	Medikal nga Unibersidad sa Vienna	Dry Eye Syndrome\|Meibomian Gland Dysfunction	Enero 8, 2018	Yugto 4
NCT01418742	Gesellschaft fur Medizinische Innovation ?Hamatologie ug Onkologie mbH\|ClinAssess GmbH	Colorectal Carcinoma	Agosto 2011	Yugto 2
NCT00980148	National Institute of Allergy and Infectious Diseases (NIAID)	Impeksyon sa Chlamydial	Disyembre 2009	Yugto 3
NCT03342456	Ang Ikatulong Xiangya Hospital sa Central South University\|Livzon Pharmaceutical Group Inc.\|Yung Shin Pharm.Ind. Co., Ltd.	Duodenal Ulcer Tungod sa Helicobacter Pylori	Disyembre 13, 2017	Yugto 4
NCT04310930	Ang University of Queensland\|Australian Government Department of Health\|Children's Hospital Foundation\|Cystic Fibrosis Foundation\|Newcastle University\|Griffith University\|Erasmus Medical Center\|Monash University\|University of Copenhagen\|Hôpital Cochin\|South Australian Health and Medical Research Institute\|University sa Melbourne\|James Cook University, Queensland, Australia\|Murdoch Childrens Research Institute	Sakit sa Pulmonary Tungod sa Mycobacteria (Diagnosis)	Marso 2020	Phase 2\|Phase 3
NCT03709459	Kirby Institute\|South Australian Health ug Medical Research Institute\|Monash University	Paglikay sa STI	Disyembre 17, 2019
NCT04067011	Emergent BioSolutions\|Biomedical Advanced Research and Development Authority	Anthrax	Agosto 12, 2019	Yugto 2
NCT02844634	British Columbia Center alang sa Pagdumala sa Sakit	HIV\|Sipilis	Mayo 15, 2018	Yugto 4
NCT00647959	Mylan Pharmaceuticals	Himsog	Marso 2006	Yugto 1
NCT00170222	Medical Center Alkmaar	Laygay nga Obstructive Pulmonary Disease	Hulyo 2002	Yugto 4
NCT03075891	Galderma	Rosacea	Hulyo 5, 2017	Yugto 4
NCT00031499	National Institute of Allergy and Infectious Diseases (NIAID)	Syphilis	Hunyo 2000	Yugto 3
NCT01205464	Unibersidad sa Linkoeping	Kakapoy\|Radicular Pain\|Cognitive Dysfunction\|Paresthesia\|Paresis	Pebrero 2005	Dili Magamit
NCT01301586	Nexgen Dermatologics, Inc.	ACNE VULGARIS	Nobyembre 2010	Phase 1\|Phase 2
NCT02305940	Imperial College sa London	Chronic Obstructive Pulmonary Disease (COPD)	Hulyo 2014	Yugto 3
NCT00351182	Dong-Min Kim\|Chosun University Hospital	Scrub Typhus	Septiyembre 2005	Yugto 3
NCT03334682	Nantes University Hospital	Acne vulgaris	Enero 31, 2018	Yugto 3
NCT01788215	Unibersidad sa Rochester	Polycystic Ovarian Syndrome (PCOS)\|Iregular nga Siklo sa Pagregla\|Sobra sa Androgen	Nobyembre 2010	Yugto 3
NCT03076281	Sidney Kimmel Cancer Center sa Thomas Jefferson University\|Thomas Jefferson University	Larynx\|LIP\|Oral Cavity\|Pharynx	Abril 3, 2017	Yugto 2
NCT00439166	Hamilton Health Sciences Corporation\|The Physicians' Services Incorporated Foundation\|McMaster University	Sakit nga Alzheimer	Pebrero 2007	Yugto 3
NCT02463942	University Medical Center Ljubljana\|University of Ljubljana School of Medicine, Slovenia	Tick-borne Encephalitis	Septiyembre 2014	Dili Magamit
NCT00803842	Northwestern University	Dili Gamay nga Cell Lung Cancer	Oktubre 2008	Dili Magamit
NCT02086591	Unibersidad sa Rochester	Adult Diffuse Large B-Cell Lymphoma\|Mantle Cell Lymphoma Nagbalikbalik\|Lymphoma, Follicular\|Marginal Zone B-Cell Lymphoma\|Malignant Lymphoma - Lymphoplasmacytic\|Waldenstrom Macroglobulinemia\|Small Lymphocytic Lymphoma\|Chronic Lymphocytic Lymphoma (CLL) Lymphoma	Marso 2014	Yugto 2
NCT03980223	University of California, San Francisco\|University of Washington\|National Institute of Allergy and Infectious Diseases (NIAID)\|Mayne Pharma International Pty Ltd\|San Francisco Department of Public Health	Gonorrhea\|Chlamydia\|Syphilis	Nobyembre 26, 2019	Yugto 4
NCT00355459	University of Texas Southwestern Medical Center	Dry Eye Syndrome	Agosto 2005	Dili Magamit
NCT01254799	Omar Mamdouh Shaaban\|Assiut University	Uterine Hemorrhage	Enero 2008	Yugto 3
NCT01547325	NanoSHIFT LLC\|Departamento sa Depensa sa Estados Unidos	Dehisced Surgical Samad	Mayo 2012	Dili Magamit
NCT00653380	Par Pharmaceutical, Inc.\|Anapharm	Aron Madeterminar ang Bioequivalence Ubos sa mga Kondisyon sa Pagpuasa	Septiyembre 1999	Yugto 1
NCT00635609	Warner Chilcott	Acne vulgaris	Marso 2008	Yugto 4
NCT03765931	Institut de Recherche pour le Developpement	Hilanat	Hulyo 2016	Yugto 4
NCT01160640	Harold Wiesenfeld\|National Institute of Allergy and Infectious Diseases (NIAID)\|University of Pittsburgh	Pelvic Inflammatory Disease	Nobyembre 2010	Yugto 2
NCT01756833	Unibersidad sa Maryland, Baltimore\|National Institute on Aging (NIA)	Aneurysm	Mayo 2013	Yugto 2
NCT00688064	Galderma	Grabe nga Acne Vulgaris	Agosto 2008	Yugto 3
NCT01320033	Galderma	Acne vulgaris	Marso 29, 2011	Yugto 2
NCT03397004	St. Michael's Hospital, Toronto\|Barrow Neurological Institute\|Duke University\|Feinstein Institute for Medical Research\|University of Pittsburgh\|Sunnybrook Health Sciences Center	Hereditary Hemorrhagic Telangiectasia (HHT)	Septiyembre 12, 2018	Yugto 2
NCT01635530	Turku University Hospital	Lyme Neuroborreliosis	Agosto 2012	Yugto 4
NCT03727620	Unibersidad sa Mohammed V Souissi	Agresibo nga Periodontitis	Enero 6, 2014	Phase 1\|Phase 2
NCT02688738	Rothman Institute Orthopedics	Propionibacterium	Marso 2015	Dili Magamit
NCT00358462	Unibersidad sa Washington\|National Institute of Allergy and Infectious Diseases (NIAID)	Uretritis	Enero 2007	Yugto 3
NCT02864550	British Columbia Center alang sa Pagdumala sa Sakit	Syphilis\|Mga Impeksyon nga Napasa sa Sekswal	Agosto 15, 2019	Yugto 4
NCT01595594	Unibersidad sa Sao Paulo\|Fundação de Amparo à Pesquisa do Estado de São Paulo	Sakit nga Periodontal\|Type 2 Diabetes	Marso 2010	Yugto 3
NCT00964834	PharmAthene, Inc.\|National Institutes of Health (NIH)\|Medarex\|Quintiles, Inc.\|Departamento sa Panglawas ug Human Services	Anthrax	Hulyo 2009	Yugto 1
NCT01809444	Unibersidad sa Sun Yat-sen	Thyroid Associated Opthalmopaties	Nobyembre 2012	Phase 2\|Phase 3
NCT01590082	MD Anderson Cancer Center\|National Institutes of Health (NIH)\|National Cancer Institute (NCI)	Melanoma	Nobyembre 2012	Phase 1\|Phase 2
NCT00207584	Mga Sentro alang sa Pagpugong ug Paglikay sa Sakit	Espesye sa tanom nga bulak ang Mycoplasma Pneumoniae	Enero 1994	Dili Magamit
NCT00775177	Ranbaxy Laboratories Limited\|Ranbaxy Inc.	Himsog	Hunyo 2005	Dili Magamit
NCT03462329	University Medical Center Ljubljana	Erythema Migrans	Hunyo 1, 2018	Dili Magamit
NCT00000403	Indiana University\|National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)\|National Institute on Aging (NIA)	Osteoarthritis	Septiyembre 1996	Yugto 3
NCT03508232	Unibersidad sa Alberta\|Royal Alexandra Hospital	ST Segment Elevation Myocardial Infarction\|Kapakyasan sa Kasingkasing	Enero 6, 2020	Yugto 2
NCT02553473	Sorlandet Hospital HF	Neuroborreliosis, Borrelia Burgdorferi	Oktubre 2015	Yugto 3
NCT02207556	Medical College sa Wisconsin	Panguna nga Systemic amyloidosis	Oktubre 1, 2014	Yugto 2
NCT01783106	Royal Liverpool University Hospital\|National Association for Colitis and Crohn's Disease\|National Institute for Health Research, United Kingdom	Sakit ni Crohn	Pebrero 1, 2014	Yugto 2
NCT00353743	Hospital de Clinicas de Porto Alegre	Aborsyon, Septic	Mayo 2006	Dili Magamit
NCT01727973	Unibersidad sa Sun Yat-sen	Graves Ophthalmopathy\|Mga Sakit sa Graves\|Mga Sakit sa Mata\|Mga Sakit sa Thyroid\|Mga Sakit sa Sistema sa Endocrine\|Mga Sakit sa Mata, Panulundon\|Hyperthyroidism\|Mga Sakit sa Autoimmune\|Mga Sakit sa Immune System	Oktubre 2012	Phase 1\|Phase 2
NCT00857038	Medical Center Alkmaar\|Leiden University Medical Center\|University of Amsterdam	Laygay nga Obstructive Pulmonary Disease\|Inflammation\|Pulmonary Emphysema	Abril 2009	Yugto 4
NCT02774993	National University Hospital, Singapore\|Tan Tock Seng Hospital\|National University, Singapore\|A*Star	Tuberculosis	Septiyembre 2015	Yugto 2
NCT03474458	IRCCS Policlinico S. Matteo	Cardiac AL amyloidosis	Pebrero 11, 2019	Phase 2\|Phase 3
NCT02874430	Sidney Kimmel Cancer Center sa Thomas Jefferson University\|Thomas Jefferson University	Breast Carcinoma\|Endometrial Clear Cell Adenocarcinoma\|Endometrial Serous Adenocarcinoma\|Uterine Corpus Cancer\|Uterine Corpus Carcinosarcoma	Hunyo 8, 2016	Yugto 2
NCT00016835	Unibersidad sa Michigan\|National Institute of Dental and Craniofacial Research (NIDCR)	Sakit nga Periodontal\|Diabetes Mellitus, Type 2	Oktubre 17, 2001	Yugto 2
NCT00064766	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	Pagdugo sa Endometrial\|Periodontal Disease	Pebrero 2003	Yugto 4
NCT00803452	Unibersidad sa Louisville	Blepharitis	Hulyo 2008	Yugto 4
NCT01434173	Bayer\|RTI Health Solutions	Samad sa Atay Tungod sa Droga	Hulyo 2001
NCT00126204	Barnes-Jewish Hospital	Aortic Aneurysm	Marso 2004	Dili Magamit
NCT01917721	Hawaii Pacific Health	Sakit sa Kawasaki\|Coronary Aneurysm	Oktubre 2013	Yugto 2
NCT02775695	Medical College sa Wisconsin	Matangtang nga Pancreatic Cancer	Abril 3, 2017	Yugto 2
NCT03824340	Aljazeera Hospital	Pagkabaog	Enero 30, 2019	Dili Magamit
NCT01847976	Ottawa Hospital Research Institute\|Canadian Breast Cancer Foundation	Sakit	Agosto 2013	Yugto 2
NCT02850913	Makerere University\|Universidad sa Oxford	Mga pag-atake	Septiyembre 5, 2016	Yugto 2
NCT00764361	NanoSHIFT LLC	Ulser sa tiil sa diabetes	Enero 2009	Yugto 2
NCT02036528	Royer Biomedical, Inc.	Mga Ulser sa tiil sa Diabetic	Enero 2014	Phase 1\|Phase 2
NCT01661985	Konseho sa Ostergotland County, Sweden\|Statens Serum Institut	Urethritis\|Cervicitis\|Infection sa Genital Mycoplasma\|Chlamydia Trachomatis	Pebrero 2010	Yugto 4
NCT01380483	Par Pharmaceutical, Inc.\|Anapharm	Aron Madeterminar ang Bioequivalence Ubos sa mga Kondisyon sa Pagpuasa	Enero 2000	Yugto 1
NCT00648180	Mylan Pharmaceuticals	Himsog	Hulyo 2005	Yugto 1
NCT01426269	Galderma Laboratories, LP	Rosacea	Septiyembre 2011	Yugto 4
NCT02753426	Unibersidad sa California, San Francisco	Laygay nga Sakit sa Bato\|Cardiorenal Syndrome	Abril 2016	Yugto 1
NCT02583282	Postgraduate nga Institute of Medical Education ug Research	Malignant nga Pleural Effusion	Agosto 1, 2015	Dili Magamit
NCT02927496	Ang Task Force for Global Health\|United States Agency for International Development (USAID)	Lymphedema\|Lymphatic Filariasis\|Filariasis	Hunyo 19, 2018	Yugto 3
NCT00652795	Par Pharmaceutical, Inc.\|Anapharm	Aron Madeterminar ang Bioequivalence Ubos sa mga Kondisyon sa Pagpuasa	Hulyo 2004	Yugto 1
NCT03956212	University Medical Center Ljubljana\|University of Ljubljana School of Medicine, Slovenia	Erythema Migrans	Hunyo 1, 2017	Dili Magamit
NCT00855595	Bayer	Papulopustular Rosacea	Pebrero 2009	Yugto 4
NCT03457636	Derm Research, PLLC	bugasbugas	Marso 19, 2018	Yugto 4
NCT02894268	Sir Run Run Shaw Hospital	Impeksyon sa Helicobacter Pylori	Pebrero 2016	Yugto 4
NCT03465774	MD Anderson Cancer Center\|National Cancer Institute (NCI)	Malignant nga Pleural Effusion	Marso 8, 2018	Unang Phase 1